美高梅簡介

    美高梅4686高等研究院是美高梅4686新成立的一個包含本科與研究生培養、側重跨學科教學與研究的校內綜合辦學單位。作為美高梅4686內部探索全面改革創新的學術特區,高等研究院與香港和海外著名高校合作,借鑒國外研究型大學通行的管理模式,引進具有一流視野的資深教授和發展潛力的青年教師,營造與國際接軌的學術氛圍和培養環境,開展卓越的教學、研究和管理工作。 ······

研究生課程

黃裕謙

博士,助理教授

聯系方式: [email protected]

通訊地址: 美高梅4686辦公樓

個人Google citation網頁:

https://scholar.google.com/citations?user=M5j3ZiQAAAAJ&hl=ja&authuser=1


教育背景:

2012 香港科技大學, 生物學, 博士

2007 香港科技大學, 生物學, 學士(榮譽、甲等)


工作經歷:

2018.6-2018.9 臺灣臺北中央研究院生物多樣性中心, 訪問學者

2015.5-2018.4 日本秋田市秋田縣立大學, 特聘助理教授

2012.3-2015.3 香港科技大學, 博士后研究員


研究興趣:

海洋無脊椎污損(固著)生物的幼體附著基因調控機制

海洋無脊椎動物(海綿, 珊瑚, 苔蘚蟲, 藤壺, 深海貽貝)共生細菌群落

藤壺外殼形成和附著凝膠粘貼機制


所獲獎項:

香港特別行政區尤德爵士紀念基金, 獎學金

香港科技大學, 院長名單


會議報告:

特邀演講

2018. 4, Tokyo University Biomineralization Seminar, Tokyo, Japan.

報告題目: Understanding barnacle shell formation from developmental and molecular perspectives.

2018. 3, Symposium of marine sessile organism 2018, Tokyo, Japan.

報告題目: アカフジツボの幼稚體における殻形成過程の解析 (Towards understanding the shell formation process of the early juvenile of the barnacle Megabalanus rosa).

2017. 10, The 14th International Symposium on Biomineralization (BIOMIN XIV), Tsukuba, Japan

報告題目: Comprehensive profiling of barnacle shell proteins by an integrated transcriptomic and proteomic approach.

2017. 10, Symposium of marine sessile organism 2017, Tokyo, Japan.

報告題目: The importance of integrating "Omics" approaches and comparative analysis in the study of novel proteins in fouling organisms: a case study on Megabalanus rosa shell formation.

大會報告

2017. 6, The 19th Marine Biotechnology Meeting, Sendai, Japan.

報告題目: 寄生性フジツボのインテルナに特異的高発現するペプチドホルモンの探索 (Exploration of peptide hormone that were specifically expressed in the interna of the parasitic barnacle Sacculina yatsui).

2012. 3, The 10th Larval Biology Symposium, Jul 28-Aug 3, 2012, Berkeley, California, USA.

報告題目: Transcriptome analysis of the bryozoan Bugula neritina.

2011. 8, 12th International congress on amino acids, peptides, and proteins, Beijing, China.

Quantitative proteomics identify molecular targets that are crucial in metamorphosis of the marine bryozoan Bugula neritina.

2009. 8, 11th International congress on amino acids, peptides, and proteins, Vienna, Austria.

報告題目: A study on metamorphosis of a marine invertebrate, the bryozoan Bugula neritina, by 2DE based proteomic approach.


論文發表:

書本章節

Okano K, Wong YH, Takahashi Y, Kikuchi A, Nogata Y, and Oguro-Okano M, Chapter 5 - Larval Cementation in the Barnacles, Megabalanus Rosa, In Barnacles: Recent Progress in Biology and Antifouling, edited by Ryusuke Kado, Haruo Mimura and Noriyuki Endo. Nova Science Publishers, Inc. March, 2018. ISBN: 978-1-53613-444-5.

學術會議論文集

Wong YH, Ozakia N, Zhang WP, Sun J, Yoshimura E, Oguro-Okano M, Nogata Y, Lin HC, Chan BKK, Qian PY, Okano K. Identification of barnacle shell proteins by transcriptome and proteomic approaches, In Biomineralization - From Molecular and Nano-structural Analyses to Environmental Science, edited by Kazuyoshi Endo, Toshihiro Kogure and Hiromichi Nagasawa. Springer Nature Singapore Pte Ltd. In press.

代表著作 (*: 共同第一作者)

Yang XX*, Wong YH*, Zhang Z*, Zhang G, Qian PY. The regulatory role of nitric oxide and NO-p38 MAPK/cGMP pathway in the larval settlement of the bryozoan Bugula neritina. Biofouling 2018, In press.

Wong YH, Yu L, Zhang G, He LS, Qian PY. In silico prediction of neuropeptides/peptide Hormone transcripts in the Cheilostome bryozoan Bugula neritina. PLoS One 2016, 11(8): e0160271.

Wong YH, Sun J, He LS, Chen LG, Qiu JW, Qian, PY. High-throughput transcriptome sequencing of the cold seep mussel Bathymodiolus platifrons. Sci Rep. 2015, 5:16597.

Wong YH, Ryu T, Seridi L, Ghosheh Y, Bougouffa S, Qian PY, Ravasi T. Transcriptome analysis elucidates key developmental components of bryozoan lophophore development. Sci Rep. 2014, 4: 6534.

Wong YH, Wang H, Ravasi T, Qian PY. Involvement of Wnt signaling pathways in the metamorphosis of the bryozoan Bugula neritina. PLoS One 2012, 7(3): e33323.

Zhang H*, Wong YH* Wang H*, Chen ZF, Arellano SM, Ravasi T, Qian PY. Quantitative proteomics identify molecular targets that are crucial in larval settlement and metamorphosis of Bugula neritina. J Proteome Res. 2010, 10(1):349-360.

Wong YH, Arellano SM, Zhang H, Ravasi T, Qian PY. Dependency on de novo protein synthesis and proteomic changes during metamorphosis of the marine bryozoan Bugula neritina. Proteome Sci. 2010, 8:25.

海洋無脊椎動物生物學

Kobayashi M, Wong YH, Oguro-Okano M, Dreyer N, H?eg JT, Yoshida R, Okano K. Identification, characterization, and larval biology of a rhizocephalan barnacle, Sacculina yatsui Boschma, 1936, from northwestern Japan (Cirripedia: Sacculinidae). J Crustacean Biol. 2018, In press. (期刊影響因子: 1.064)

Yang XX, Zhang Y, Wong YH, Qian PY. HSP90 regulates larval settlement of the bryozoan Bugula neritina through NO pathway. J Exp Biol 2018, jeb-167478.

Zhang Y, Yang XX, Wong YH, Qian PY. The regulatory role of arginine kinase during larval settlement of the bryozoan Bugula neritina. Mar Biol. 2018, 165(3):52.

Lan Y, Sun J, Tian R, Bartlett DH, Li R, Wong YH, Zhang W, Qiu JW, Xu T, He LS, Tabata HG, Qian PY. Molecular adaptation in the world's deepest‐living animal: Insights from transcriptome sequencing of the hadal amphipod Hirondellea gigas. Mol Ecol. 2017, 26(14): 3732-3743.

Zhang G, Yan GY, Yang XX, Wong YH, Sun J, Zhang Y, He LS, Xy Y, Qian PY. Characterization of arginine kinase in the barnacle Amphibalanus amphitrite and its role in the larval settlement. J Exp Zool B 2016, 326(4): 237-249.

Zhang G, He LS, Wong YH, Xu Y, Zhang Y, Qian PY. p38 MAPK regulates PKAα and CUB-serine protease in Amphibalanus amphitrite cyprids. Sci Rep. 2015, 5:14767.

Zhang G, He LS, Wong YH, Xu Y, Zhang Y, Qian PY. Chemical Component and Proteomic Study of the Amphibalanus (= Balanus) amphitrite Shell. PLoS One 2015, 10(7):e0133866.

Zhang G, He LS, Wong YH, Yu L, Qian PY. siRNA transfection in larvae of the barnacle Amphibalanus amphitrite. J Exp Biol. 2015, 218(16):2505-2509.

Lin HC, Wong YH, Tsang LM, Chu KH, Qian PY, Chan BKK. First study on gene expression of cement proteins and potential adhesion-related genes of a membranous-based barnacle as revealed from Next-Generation Sequencing technology. Biofouling 2014, 30(2):169-181.

Chen ZF, Zhang H, Wang H, Matsumura K, Wong YH, Ravasi T, Qian PY. Quantitative proteomics study of larval settlement in the barnacle Balanus amphitrite. PLoS One 2014, 9(2): e88744.

Zhang G, He LS, Wong YH, Qian PY. MKK3 was Involved in larval settlement of the barnacle Amphibalanus amphitrite through activating the kinase activity of p38MAPK. PLoS One 2013, 8(7):e69510.

Chandramouli, KH, Zhang Y, Wong YH, Qian PY. Comparative glycoproteome analysis: Dynamics of protein glycosylation during metamorphic transition from pelagic to benthic life stages in three invertebrates. J Proteome Res. 11(2):1330-1340. 2011.

Wang H, Zhang H, Wong YH, Voolstra C, Ravasi T, Bajic V, Qian PY. Rapid transcriptome and proteome profiling of a non-model marine invertebrate, Bugula neritina. Proteomics 2010, 10(16):2972-2981.

Qian PY, Wong YH, Zhang Yu. Changes in the proteome and phosphoproteome expression in the bryozoan Bugula neritina larvae in response to the antifouling agent butenolide. Proteomics 2010, 10(19):3435-3446.

Thiyagarajan V, Wong T, Qian PY. 2D gel-based proteome and phosphoproteome analysis during larval metamorphosis in two major marine biofouling invertebrates. J Proteome Res. 2009, 8(6): 2708-2719.

海洋微生物生態學

Cai L, Tian RM, Zhou G, Tong H, Wong YH, Zhang W, Chui APY, James Y. Xie, Xia J, Qiu JW, Ang PO, Liu S, Huang H, Qian PY. Exploring coral microbiome assemblages in the South China Sea. Sci Rep. 2018, 8(1):2428.

Cai L, Zhou G, Tian RM, Tong H, Zhang W, Sun J, Ding W, Wong YH, Xia J, Qiu JW, Liu S, Huang H, Qian PY. Metagenomic analysis reveals a green sulfur bacterium as a potential coral symbiont. Sci Rep. 2017, 7(1):9320.

Tian RM, Zhang W, Cai L, Wong YH, Ding W, Qian PY. Genome Reduction and Microbe-Host Interactions Drive Adaptation of a Sulfur-Oxidizing Bacterium Associated with a Cold Seep Sponge. mSystems 2017, 2(2): e00184-16.

Gao ZM, Wang Y, Tian RM, Lee OO, Wong YH, Batang ZB, Al-Suwailem A, Lafi FF, Bajic VB, Qian PY. Pyrosequencing revealed shifts of prokaryotic communities between healthy and disease-like tissues of the Red Sea sponge Crella cyathophora. PeerJ 2015, 3:e890.

Zhang W, Wang Y, Bougouffa S, Tian RM, Cao HL, Li YX, Cai L, Wong YH, Zhang G, Zhou G. Synchronized dynamics of bacterial niche specific functions during biofilm development in a cold seep brine pool. Environ Microbiol. 2015, 17(10):4089-4104.

Gao ZM, Wang Y, Tian RM, Wong YH, Batang ZB, Al-Suwailem AM, Bajic VB, Qian PY. Symbiotic Adaptation Drives Genome Streamlining of the Cyanobacterial Sponge Symbiont “Candidatus Synechococcus spongiarum”. MBio 2014, 5(2):e00079-14.

Gao ZM, Wang Y, Lee OO, Tian RM, Wong YH, Bougouffa S, Batang, Zenon; Al-Suwailem A, Lafi FF, Bajic VB. Pyrosequencing reveals the microbial communities in the Red Sea sponge Carteriospongia foliascens and their impressive shifts in abnormal tissues. Microbial Ecol. 2014, 68(3):621-632.

Wang Y, Zhang WP, Cao HL, Shek CS, Tian RM, Wong YH, Batang ZB, Al-Suwailem A, Qian PY. Diversity and distribution of eukaryotic microbes in and around a brine pool adjacent to the Thuwal cold seeps in the Red Sea. Front Microbiol. 2014, 5:37.

Zhang WP, Wang Y, Tian RM, Bougouffa S, Yang B, Cao HL, Zhang G, Wong YH, Xu W, Batang ZB. Species sorting during biofilm assembly by artificial substrates deployed in a cold seep system. Sci Rep. 2014, 4:6647.

Jin T, Zhang T, Ye L, Lee OO, Wong YH, Qian PY. Diversity and quantity of ammonia-oxidizing Archaea and Bacteria in sediment of the Pearl River Estuary, China. Appl Microbiol Biot. 2011, 90(3):1137-1145.

Yang, Jiangke; Sun, Jin; Lee OO, Wong YH, Qian, PY. Phylogenetic diversity and community structure of sponge-associated bacteria from mangroves of the Caribbean Sea. Aquat Microb Ecol. 2011, 62(3):231.

Qian PY, Wang Y, Lee OO, Lau SCK, Yang J, Lafi FF, Al-Suwailem A, Wong YH. Vertical stratification of microbial communities in the Red Sea revealed by 16S rDNA pyrosequencing. ISME J. 2011, 5(3):507-518.

Wang Y, Yang J, Lee OO, Dash S, Lau SCK, Al-Suwailem A, Wong YH, Danchin A, Qian PY. Hydrothermally generated aromatic compounds are consumed by bacteria colonizing in Atlantis II Deep of the Red Sea. ISME J. 2011, 5(10):1652-1659.

Lee OO, Chui, Pui Yi; Wong YH, Pawlik, Joseph R; Qian PY. Evidence for vertical transmission of bacterial symbionts from adult to embryo in the Caribbean sponge Svenzea zeai. Appl Environ Microbiol. 2009, 75(19):6147-6156.

Lee OO, Wong YH, Qian PY. Inter-and intraspecific variations of bacterial communities associated with marine sponges from San Juan Island, Washington. Appl Environ Microbiol. 75(11):3513-3521. 2009.

防污研究和毒理學

Huang XZ, Xu Y, Zhang YF, Zhang Y, Wong YH, Han Z, Yin Y, Qian PY. Nontoxic piperamides and their synthetic analogues as novel antifouling reagents. Biofouling 2014, 30(4):473-481.

Chen L, Zhang H, Sun J, Wong YH, Han Z, Au DWT, Bajic VB, Qian PY. Proteomic changes in brain tissues of marine medaka (Oryzias melastigma) after chronic exposure to two antifouling compounds: Butenolide and 4, 5-dichloro-2-n-octyl-4-isothiazolin-3-one (DCOIT). Aquat Toxicol. 2014, 157:47-56.

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